LONG TERM EVALUATION OF CHEMOTHERAPY IN CYSTIC

ECHINOCOCCOSIS

 

PATIENT

Age

Sex

Time of diagnosis

 

CYST

Localization

Diameter(cm.)

Age of cyst (presumed) (in years)

Cyst morphology(WHO standardized classification)

FIRST TREATMENT

Drug

Dosage

Months of administration

Continuous/Intermittent treatment

Degenerative modification of cyst after 1 treatment:

 

 

 

 

 

 

Side effects observed during first treatment

 

 

 

 

 

Disappearing of cyst

Volumetric reduction

Detachment of membranes

Partial solidification

Total solidification

Calcification

 

RELAPSE

No

Yes

Morphology of relapsed cyst

 

 

 

Months between stopping treatment and relapse:

 

 

 

Appearance of (a) new cyst(s)

Volumetric increase of the cyst

New daughter cysts

Disappearing of detachment of membranes

SECOND TREATMENT

Drug

Dosage

Months of administration

Continuous/Intermittent treatment

Degenerative modification of cyst ater 2 treatment

 

 

 

 

 

Side effects observed during second treatment

PAIR

Surgery

Wait and watch management

 

 

 

 

 

Disappearing of cyst

Volumetric reduction

Detachment of membranes

Partial solidification

Total solidification

Calcification

 

THIRD TREATMENT

Morphology of further relapse

Months between stopping treatment and relapse:

Drug

Dosage

Months of administration

Continuous/Intermittent treatment

Degenerative modification of cyst ater 3 treatment

 

 

 

 

Side effects observed during third treatment

PAIR

Surgery

Wait and watch management

 

 

 

 

 

 

 

 

Disappearing of cyst

Volumetric reduction

Detachment of membranes

Partial solidification

Total solidification

Calcification

 

FOURTH TREATMENT

Morphology of further relapse

Months between stopping treatment and relapse:

Drug

Dosage

Months of administration

Continuous/Intermittent treatment

Degenerative modification of cyst ater 4 treatment

 

 

 

 

Side effects observed during fourth treatment

PAIR

Surgery

Wait and watch management

 

 

 

 

 

 

 

 

Disappearing of cyst

Volumetric reduction

Detachment of membranes

Partial solidification

Total solidification

Calcification

 

FIFTH TREATMENT

Morphology of further relapse

Months between stopping treatment and relapse:

Drug

Dosage

Months of administration

Continuous/Intermittent treatment

Degenerative modification of cyst ater 5 treatment

 

 

 

 

 

Side effects observed during fifth treatment

PAIR

Surgery

Wait and watch management

 

 

 

 

 

 

 

Disappearing of cyst

Volumetric reduction

Detachment of membranes

Partial solidification

Total solidification

Calcification

FURTHER RELAPSES

NO

YES

PAIR

Surgery

Wait and watch management